KNOWLEDGE

The science behind the practice

Physician-authored explanations of the biomarkers, tests, and ideas that shape modern preventive medicine — written to be rigorous, not dumbed down.

Preventive Medicine

8 min

Bone Density Test: What the T-Score Says, and What It Leaves Out

A bone density scan grades your bones — but most fractures happen above the osteoporosis threshold. How to read the T-score, and what lowers fracture risk.

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Cardiovascular

7 min

Blood Pressure Targets: Why the Real Number Comes From Home Monitoring

Age-based blood pressure charts mislead. Learn the real home and clinic thresholds, a 7-day measurement protocol, and how your target follows total risk.

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Cancer

8 min

PSA Test: What a Raised Result Means Before You Agree to a Biopsy

A raised PSA test is a finding, not a diagnosis. What lifts the number, why the first value rarely decides, and why MRI should come before biopsy.

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Cardiovascular

9 min

Statin Side Effects: How to Tell Whether the Drug Is Really the Cause

Muscle pain on a statin is real — but blinded trials show the drug is often not the cause. How to test it properly, and what to do if intolerance is genuine.

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Hormonal

8 min

Menopause Hormone Therapy: Why Timing Changes the Whole Answer

The 2002 WHI headline still shapes the advice women get. What menopause hormone therapy treats, what it does not, and when timing makes you a candidate.

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Cardiovascular

8 min

Coronary Calcium Score: Who It Helps, and Who Should Skip It

A coronary calcium score settles one decision: whether to start lipid-lowering therapy. What zero really means, what a high score changes, and who can skip it.

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Metabolic

8 min

Fatty Liver: Not How Much Fat, but Whether Scarring Has Already Begun

Mild fatty liver on an ultrasound is a metabolic finding, not a liver verdict. FIB-4, from labs already in your file, shows whether fibrosis is the real risk.

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Metabolic

8 min

GLP-1 Weight Loss: What to Measure Before the First Injection

Ozempic, Wegovy and Mounjaro change far more than weight. What to measure before the first injection, what to track after, and the exit question nobody asks.

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Preventive Medicine

8 min

What an Executive Checkup in Israel Finds — and the Question It Never Asks

The Israeli executive checkup is thorough at answering one question: is there disease now. Here is the second question it was never designed to ask.

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Preventive Medicine

9 min

Comprehensive Blood Panel: What Yours Misses, and What Is Wasted On It

Thirty normal rows is not a comprehensive blood panel. Which markers yours omits, what changes clinically when they are abnormal, and what is wasted.

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Preventive Medicine

9 min

Screening Tests by Age: What Belongs on Your List in Each Decade

A decade-by-decade guide to screening tests by age in Israel: which ones actually change outcomes, what the health funds already cover, and when to stop.

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Preventive Medicine

10 min

Whole-Body MRI: What It Finds, and What It Misses

A whole-body MRI sees the tumours no screening programme looks for — and misses the cancers most likely to harm you. How to decide, in the Israeli context.

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Preventive Medicine

8 min

Biological Age Tests: What the Number Can and Cannot Tell You

Epigenetic clocks, glycans and proteomics promise a biological age in one number. What the evidence supports, what it does not, and what to measure instead.

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Cardiovascular

8 min

CIMT: Why a Normal Stress Test Doesn't Rule Out Plaque

Atherosclerosis begins decades before symptoms, and stress tests only detect late disease. What carotid ultrasound shows, how it compares to coronary calcium, and what changes when plaque is found.

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Cardiovascular

9 min

Lp(a): The Inherited Risk Factor Almost Nobody Measures

One adult in five carries an elevated Lp(a). It is set by genetics, stable for life, absent from every standard lipid panel — and it explains a great deal of premature heart disease.

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Metabolic

9 min

CGM Without Diabetes: What 14 Days of Glucose Data Reveal

A fasting glucose is one number from a state you never live in. Fourteen days of continuous data show the post-meal physiology that fails years before HbA1c moves — and where hype outruns evidence.

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Body Composition

8 min

Visceral Fat: Why Body Composition Beats the Bathroom Scale

Two people can share the same BMI and weight while only one is metabolically healthy. What visceral fat does to the liver — and why body composition, not the scale, is the measurement that matters.

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Performance

8 min

Grip Strength: The Thirty-Second Test That Predicts How You Will Age

A hand dynamometer predicts mortality better than blood pressure does. What grip strength, muscle power, and balance reveal about how you will age — and the training that reliably changes them.

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Sleep

8 min

The Sleep Apnea Most People Don't Know They Have

Obstructive sleep apnea is common, consequential, and mostly undiagnosed — and it is not only a disease of snoring, overweight men. What screening actually finds, and which treatments hold up.

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Cognitive

7 min

APOE e4 and Dementia Risk: What Is Actually Modifiable

Carrying APOE e4 raises Alzheimer risk substantially but does not determine it. What the alleles mean, whether to test at all, and the large share of dementia risk that is genuinely modifiable.

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Genetics

8 min

Pharmacogenomics: Why the Same Drug Works Differently in Different People

Inherited variation in a few enzymes and transporters decides whether clopidogrel works, whether a statin causes muscle pain, and whether codeine is dangerous — and what a panel cannot tell you.

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Cancer

9 min

Early Cancer Detection: What Works and What Is Oversold

Stage at diagnosis decides most cancer outcomes. Which screening actually reduces deaths, what multi-cancer blood tests and whole-body MRI can and cannot do, and why survival statistics mislead.

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Cardiovascular

6 min

Why ApoB Matters More Than LDL-C

LDL-C is the number on most lab reports. ApoB is the number that actually predicts risk. Here is why the distinction matters — and what your ApoB reveals about your arterial health.

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Performance

7 min

VO₂max: The Number That Predicts How Long You'll Live

Cardiorespiratory fitness predicts all-cause mortality better than smoking, diabetes, or hypertension. What the data shows — and how to train the most responsive longevity biomarker we have.

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Metabolic

5 min

What Your Fasting Insulin Reveals That HbA1c Doesn't

HbA1c can look normal while metabolic dysfunction is already underway. Fasting insulin is the earlier, more sensitive signal — and it is almost never on a standard lab panel.

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Hormonal

9 min

Testosterone, Thyroid, and the Space Between Normal and Optimal

Few tests are misread as often as a hormone panel. Why low testosterone is usually a symptom of something else, when a borderline TSH warrants treating, and what a reference range never tells you.

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